RAF Typhoon jets have operated alongside French warplanes in a joint strike against an subterranean weapons facility in Syria used by the IS group, per a report from the UK's MoD.
The location, identified by reconnaissance, was thought to be housing weapons and explosive materials, the statement said, and was situated in hills just north of the ancient city of Palmyra in the heart of Syria.
"Our aircraft employed laser-guided Paveway IV weapons to strike a series of approach shafts leading to the facility... preliminary assessments indicate the objective was successfully hit," the ministry announced.
There was no evidence of any civilian casualties in the attack late on Saturday and all the aircraft returned safely, the MoD added.
The Typhoon fighters were assisted by a Voyager refuelling tanker.
Daesh - also known as Daesh - enforced extremist governance over parts of Iraq and Syria prior to its 2019 collapse.
"This strike shows the UK's leading role, and resolve to operate in unison with our partners, to eliminate any revival of the terrorist group and their harmful and extremist ideologies in the area," Britain's Defence Chief John Healey said.
UK warplanes have carried out patrols over Syria to "deter any efforts to regroup" of Islamic State following its military defeat at the Baghuz confrontation in 2019, the MoD reported.
"I must thank every member of our armed forces who took part in this strike for their expertise and their bravery," Healey said. "They were part of a great many UK service members deployed over the holidays. This mission, to eliminate terrorist threats who endanger our security, highlights how our armed forces are prepared to act, throughout the year, protecting the UK domestically and strong abroad."
Last December, the United States armed forces conducted what it described as a "major assault" on Islamic State objectives in the country, subsequent to an attack claimed the lives of two US servicemembers and a civilian interpreter in Palmyra.
The United Nations reports Islamic State still maintains between 5,000 and 7,000 combatants in both countries.
